Infection · Human genetics
Why Does Disease Spare Some of Us?
A shared pathogen does not always mean a shared outcome. Genetic variation, immune responses and exposure histories all matter.
People exposed to the same pathogen can experience very different outcomes. Differences in exposure dose, prior immunity, genetics, age and underlying physiology can all contribute.
The scientific question is how to distinguish mechanisms of resistance, tolerance and reduced exposure rather than treating all asymptomatic outcomes as equivalent.
AI-assisted preliminary overview · Awaiting editorial review. The linked materials are research leads; some citations remain to be checked against the original works.